![]() This software eliminates the laborious and error-prone manual entry of data, substantially reduces the amount of time spent for data analysis. Thus, we have developed open source, free, easy-to-use software for performing standardized data evaluations and automatically calculating the IC 50. The currently available software for calculating IC 50 values requires manual data entry, is time consuming, and is prone to calculation errors. The results of these in vitro drug screening assays are commonly expressed as inhibitory concentration 50% (IC 50): the concentration of the tested agent that inhibits the proliferation of the cancer cell population to 50% of the theoretically possible effect (absolute IC 50) or maximum effect practically achieved by the drug (relative IC 50). ![]() In the process of new cancer drug development, as the first step of their assessment, their activities are usually studied in vitro against a panel of cancer cell lines.
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